The effect of increased gastrin release on lower esophageal sphincter pressure.
نویسندگان
چکیده
منابع مشابه
Effect of ginger on lower esophageal sphincter pressure.
OBJECTIVE Ginger has been traditionally used to reduce intestinal gas and flatulence. The present study examined the effects of ginger on the esophagus and lower esophageal sphincter (LES) function by esophageal manometry. STUDY DESIGN A randomized controlled trial. SETTING Departments of Physiology and Medicine, Faculty of Medicine Siriraj Hospital. SUBJECTS Fourteen healthy young male v...
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The role of gastrin in controlling lower oesophageal sphincter pressure (LESP) has been examined by measurement of LESP and serum gastrin response to a test protein solution and a control solution in humans. Both solutions were associated with significant (P less than 0-005) rise in LESP, but serum gastrin rose significantly (P=0-05) only after the protein solution. The rise in serum gastrin af...
متن کاملMechanics of sphincter action. Studies on the lower esophageal sphincter.
The purpose of this study was to evaluate the mechanical factors involved in the genesis of lower esophageal sphincter pressure. We determined the relationship between intraluminal pressure and inside diameter, estimated the ratio between the wall thickness to inside radius, and calculated the tension in the wall of the lower esophageal sphincter as a function of the inside diameter. Various de...
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Fat meals are known to decrease lower esophageal sphincter (LES) pressure, possibly through postprandial CCK release. Dietary fat consists mainly of long-chain triglycerides (LCT), which potently stimulate CCK secretion. This effect contrasts with that of medium-chain triglycerides (MCT), which do not induce CCK release. We recorded LES pressure and gallbladder volume in six healthy subjects on...
متن کاملAction of gastrin on the lower oesophageal sphincter in man.
Both hog gastrin and synthetic gastrin stimulate the cardiac sphincter to increase tone and augment the resistance to reflux. Endogenous gastrin has a similar effect, and gastrin also stimulates the secretion of acid which has also been found to increase the resistance of the sphincter, but the effect of gastrin appears to be independent of the secretory stimulus.
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ژورنال
عنوان ژورنال: The Tohoku Journal of Experimental Medicine
سال: 1984
ISSN: 0040-8727,1349-3329
DOI: 10.1620/tjem.144.377